De Clercq, Erik D.: search on Z-Library

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1

Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection

Stittelaar, Koert J., Neyts, Johan, Naesens, Lieve, van Amerongen, Geert, van Lavieren, Rob F., Holý, Antonin, De Clercq, Erik, Niesters, Hubert G. M., Fries, Edwin, Maas, Chantal

Journal:

Year:

2005

Language:

english

File:

PDF, 430 KB

english, 2005

2

STRATEGIES IN THE DESIGN OF ANTIVIRAL DRUGS

De Clercq, Erik

Journal:

Nature Reviews Drug Discovery

Year:

2002

Language:

english

File:

PDF, 4.45 MB

english, 2002

3

Suramin: A potent inhibitor of the reverse transcriptase of RNA tumor viruses

De Clercq, Erik

Journal:

Year:

1979

Language:

english

File:

PDF, 853 KB

english, 1979

4

Current and emerging non-nucleoside reverse transcriptase inhibitors (NNRTIs) for HIV-1 treatment

Wang, Yali, De Clercq, Erik, Li, Guangdi

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2019

Language:

english

File:

PDF, 1.36 MB

english, 2019

5

Relationship between the foot progression angle and eversion and exercise-related lower leg pain

Tine M Willems, Erik Witvrouw, Dirk De Clercq, Philip Roosen

Journal:

Journal of Foot and Ankle Research

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

6

Intrinsic gait-related risk factors for Achilles tendinopathy in novice runners: A prospective study

Ans Van Ginckel, Youri Thijs, Narmin Ghani Zadeh Hesar, Nele Mahieu, Dirk De Clercq, Philip Roosen, Erik Witvrouw

Journal:

Year:

2009

Language:

english

File:

PDF, 274 KB

english, 2009

7

Overview of Recent Strategic Advances in Medicinal Chemistry

Wu, Gaochan, Zhao, Tong, Kang, Dongwei, Zhang, Jian, Song, Yuning, Namasivayam, Vigneshwaran, Kongsted, Jacob, Pannecouque, Christophe, De Clercq, Erik, Poongavanam, Vasanthanathan, Liu, Xinyong, Zhan

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 3.78 MB

english, 2019

8

Synthesis, In Vitro and In Vivo Release Kinetics, and Anti-HIV Activity of A Sustained-Release Prodrug (mPEG-AZT) of 3′-Azido-3′-deoxythymidine (AZT, Zidovudine)

Dr. Wenjun Li, Yu Chang, Peng Zhan, Prof. Dr. Na Zhang, Prof. Dr. Xinyong Liu, Prof. Dr. Christophe Pannecouque, Prof. Dr. Erik De Clercq

Journal:

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

9

Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives

Johan Neyts, Erik De Clercq

Journal:

Antiviral Research

Year:

2003

Language:

english

File:

PDF, 141 KB

english, 2003

10

A 40-Year Journey in Search of Selective Antiviral Chemotherapy*

De Clercq, Erik

Journal:

Annual Review of Pharmacology

Year:

2011

Language:

english

File:

PDF, 3.90 MB

english, 2011

11

Antiviral drugs: current state of the art

Journal:

Journal of Clinical Virology

Year:

2001

Language:

english

File:

PDF, 304 KB

english, 2001

12

Suramin in the treatment of AIDS: Mechanism of action

Journal:

Antiviral Research

Year:

1987

Language:

english

File:

PDF, 499 KB

english, 1987

13

Contralateral Risk Factors Associated with Exertional Medial Tibial Pain in Women

VERRELST, RUTH, DE CLERCQ, DIRK, WILLEMS, TINE MARIEKE, ROOSEN, PHILIP, WITROUW, ERIK

Journal:

Medicine & Science in Sports & Exercise

Year:

2014

Language:

english

File:

PDF, 2.87 MB

english, 2014

14

Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends

Zhan, Peng, Pannecouque, Christophe, De Clercq, Erik, Liu, Xinyong

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 3.58 MB

english, 2015

15

Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF)

De Clercq, Erik

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 643 KB

english, 2016

16

Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs

Wang, Zhao, Yu, Zhao, Kang, Dongwei, Zhang, Jian, Tian, Ye, Daelemans, Dirk, De Clercq, Erik, Pannecouque, Christophe, Zhan, Peng, Liu, Xinyong

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

17

New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections

De Clercq, Erik

Journal:

Chemistry – An Asian Journal

Year:

2019

Language:

english

File:

PDF, 675 KB

english, 2019

18

In vitro, ex vivo, and in situ intestinal absorption characteristics of the antiviral ester prodrug adefovir dipivoxil

Pieter Annaert, Josef J. Tukker, Jan van Gelder, Lieve Naesens, Erik de Clercq, Guy van den Mooter, Renaat Kinget, Patrick Augustijns

Journal:

Journal of Pharmaceutical Sciences

Year:

2000

Language:

english

File:

PDF, 202 KB

english, 2000

19

1,2,3-Thiadiazole Thioacetanilides. Part 2 : Synthesis and Biological Evaluation of a New Series of 2-{[4-(3,4-Dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 Inhibitors

Peng Zhan, Xin-Yong Liu, Zhen-Yu Li, Zeng-Jun Fang, Christophe Pannecouque, Erik De Clercq

Journal:

Chemistry & Biodiversity

Year:

2010

Language:

english

File:

PDF, 330 KB

english, 2010

20

Synthesis and Antileishmanial Activity of (1,3-Benzothiazol-2-yl) Amino-9-(10H)-acridinone Derivatives.

Florence Delmas, Antonio Avellaneda, Carole Di Giorgio, Maxime Robin, Erik De Clercq, Pierre Timon-David, Jean-Pierre Galy

Journal:

Year:

2004

File:

PDF, 15 KB

2004

21

Activity of the keggin polyoxotungstate pm-19 against herpes simplex virus type 2 infection in immunosuppressed mice: Role of peritoneal macrophage activation

Dr. Satoru Ikeda, Shigeki Nishiya, Akihiro Yamamoto, Toshihiro Yamase, Chiaki Nishimura, Erik De Clercq

Journal:

Journal of Medical Virology

Year:

1993

Language:

english

File:

PDF, 521 KB

english, 1993

22

Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid

Tatiana Fonseca, Bárbara Gigante, M.Matilde Marques, Thomas L. Gilchrist, Erik De Clercq

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 280 KB

english, 2004

23

The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of l-ascorbic acid: Synthesis, cytostatic, and antiviral activity evaluations

Tatjana Gazivoda, Silvana Raić-Malić, Marko Marjanović, Marijeta Kralj, Krešimir Pavelić, Jan Balzarini, Erik De Clercq, Mladen Mintas

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

24

Synthesis and antileishmanial activity of (1,3-benzothiazol-2-yl) amino-9-(10H)-acridinone derivatives

Florence Delmas, Antonio Avellaneda, Carole Di Giorgio, Maxime Robin, Erik De Clercq, Pierre Timon-David, Jean-Pierre Galy

Journal:

European Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 226 KB

english, 2004

25

Synthesis and biological activity of 4-thiazolidinones, thiosemicarbazides derived from diflunisal hydrazide

Güniz Küçükgüzel, Ayla Kocatepe, Erik De Clercq, Fikrettin Şahin, Medine Güllüce

Journal:

European Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 304 KB

english, 2006

26

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents

İlkay Küçükgüzel, Esra Tatar, Ş. Güniz Küçükgüzel, Sevim Rollas, Erik De Clercq

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 394 KB

english, 2008

27

Structure–activity relationships for dipeptide prodrugs of acyclovir: Implications for prodrug design

Cledir R. Santos, Rita Capela, Cláudia S.G.P. Pereira, Emília Valente, Luís Gouveia, Christophe Pannecouque, Erik De Clercq, Rui Moreira, Paula Gomes

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 389 KB

english, 2009

28

Synthesis and antiviral activity of 2-deoxy-1,5-anhydro-D-mannitol nucleosides containing a pyrimidine base moiety

María-Jesús Pérez-Pérez, Erik De Clercq, Piet Herdewijn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 210 KB

english, 1996

29

Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives

Deepika Sharma, Balasubramanian Narasimhan, Pradeep Kumar, Vikramjeet Judge, Rakesh Narang, Erik De Clercq, Jan Balzarini

Journal:

European Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 225 KB

english, 2009

30

Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones

Krishnan Suresh Kumar, Swastika Ganguly, Ravichandran Veerasamy, Erik De Clercq

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

31

Acute Encephalitis, a Poliomyelitis-like Syndrome and Neurological Sequelae in a Hamster Model for Flavivirus Infections

Pieter Leyssen, Romaric Croes, Philipp Rau, Sabine Heiland, Erik Verbeken, Raphael Sciot, Jan Paeshuyse, Nathalie Charlier, Erik De Clercq, Uta Meyding-Lamadé, Johan Neyts

Journal:

Brain Pathology

Year:

2003

Language:

english

File:

PDF, 1.15 MB

english, 2003

32

Three decades of antiviral drugs

Clercq, Erik De

Journal:

Nature Reviews Drug Discovery

Year:

2007

Language:

english

File:

PDF, 107 KB

english, 2007

33

Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses

Lieve Naesens, Chad E. Stephens, Graciela Andrei, Arianna Loregian, Leen De Bolle, Robert Snoeck, J. Walter Sowell, Erik De Clercq

Journal:

Antiviral Research

Year:

2006

Language:

english

File:

PDF, 323 KB

english, 2006

34

Antiviral Activities of New Cidofovir Analogs Against Camelpox Virus, Used as a Model of Variola Virus, in Human Skin Equivalent Cultures

Sophie Duraffour, Robert Snoeck, Joost Van Den Oord, Marcela Krecmerová, Antonín Holý, Jean-Marc Crance, Daniel Garin, Erik De Clercq, Graciela Andrei

Journal:

Antiviral Research

Year:

2007

Language:

english

File:

PDF, 61 KB

english, 2007

35

A pyrazolotriazolopyrimidinamine inhibitor of bovine viral diarrhea virus replication that targets the viral RNA-dependent RNA polymerase

Jan Paeshuyse, Carine Letellier, Matheus Froeyen, Hélène Dutartre, Robert Vrancken, Bruno Canard, Erik De Clercq, Alain Gueiffier, Jean-Claude Teulade, Piet Herdewijn, Gerhard Puerstinger, Frank Koene

Journal:

Antiviral Research

Year:

2009

Language:

english

File:

PDF, 407 KB

english, 2009

36

Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs

Shuang-Xi Gu, Shi-Qiong Yang, Qiu-Qin He, Xiao-Dong Ma, Fen-Er Chen, Hui-Fang Dai, Erik De Clercq, Jan Balzarini, Christophe Pannecouque

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 478 KB

english, 2011

37

Differential inhibition of various deoxyribonucleic acid polymerases by Evans blue and aurintricarboxylic acid

Hideo NAKANE, Jan BALZARINI, Erik de CLERCQ, Katsuhiko ONO

Journal:

Year:

1988

Language:

english

File:

PDF, 561 KB

english, 1988

38

Fluorescent Tricyclic Analogues of Acyclovir and Ganciclovir. A Structure−Antiviral Activity Study

Golankiewicz, Bozenna, Ostrowski, Tomasz, Goslinski, Tomasz, Januszczyk, Piotr, Zeidler, Joanna, Baranowski, Daniel, de Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 87 KB

english, 2001

39

Replacement of the Metabolically Labile Methyl Esters in the Alkenyldiarylmethane Series of Non-Nucleoside Reverse Transcriptase Inhibitors with Isoxazolone, Isoxazole, Oxazolone, or Cyano Substituents

Deng, Bo-Liang, Hartman, Tracy L., Buckheit,, Robert W., Pannecouque, Christophe, De Clercq, Erik, Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

40

Toward Improved Anti-HIV Chemotherapy: Therapeutic Strategies for Intervention with HIV Infections

De Clercq, Erik

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 6.27 MB

english, 1995

41

5-chloro-substituted derivatives of 2',3'-didehydro-2' ,3'-dideoxyuridine, 3'-fluoro-2' ,3'-dideoxyuridine and 3'-azido-2' ,3'-dideoxyuridine as anti-HIV agents

Jan Balzarini, Arthur Van Aerschot, Piet Herdewijn, Erik De Clercq

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 574 KB

english, 1989

42

Antiviral drugs in current clinical use

Journal:

Journal of Clinical Virology

Year:

2004

Language:

english

File:

PDF, 588 KB

english, 2004

43

Cidofovir in the therapy and short-term prophylaxis of poxvirus infections

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

44

Antiviral activity of diverse classes of broad-acting agents and natural compounds in HHV-6-infected lymphoblasts

Lieve Naesens, Pascale Bonnafous, Henri Agut, Erik De Clercq

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 572 KB

english, 2006

45

Antivirals: Past, present and future

De Clercq, Erik

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 383 KB

english, 2013

46

Synthesis and antiviral properties of 5-vinylpyrimidine nucleoside analogs

Erik De Clercq, Richard T. Walker

Journal:

Pharmacology & Therapeutics

Year:

1984

Language:

english

File:

PDF, 2.80 MB

english, 1984

47

Synthesis and antiviral activity of monofluorinated cyclopropanoid nucleosides

Rosen, Thomas C., De Clercq, Erik, Balzarini, Jan, Haufe, G�nter

Journal:

Organic & Biomolecular Chemistry

Year:

2004

Language:

english

File:

PDF, 230 KB

english, 2004

48

Organic Chemist Whose Inventions Reshaped the Antiviral Drug World

De Clercq, Erik

Journal:

Medicinal Research Reviews

Year:

2013

Language:

english

File:

PDF, 446 KB

english, 2013

49

[Methods and Principles in Medicinal Chemistry] Antiviral Drug Strategies (DE CLERCQ:ANTIVIRAL DRUGS O-BK) || Antiviral RNAi: How to Silence Viruses

De Clercq, Erik

Year:

2011

Language:

english

File:

PDF, 260 KB

english, 2011

50

HIV Inhibitors Targeted at the Reverse Transcriptase

DE CLERCQ, ERIK

Journal:

AIDS Research and Human Retroviruses

Year:

1992

Language:

english

File:

PDF, 1.99 MB

english, 1992

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